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Random mutagenesis of the thymidine kinase gene of varicella-zoster virus.

To understand the relationship between the primary structure and function of varicella-zoster virus thymidine kinase (VZV TK; EC 2.7.1.21), we established rapid screening and phenotypic selection of mutant VZV TK genes in TK-deficient Escherichia coli C600 by using a constitutive pKK223-3 expression...

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Dades bibliogràfiques
Publicat a:J Virol
Autors principals: Suzutani, T, Lacey, S F, Powell, K L, Purifoy, D J, Honess, R W
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 1992
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC289003/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1312622/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.66.4.2118-2124.1992
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