Phosphorylation of four acyclic guanosine analogs by herpes simplex virus type 2 thymidine kinase.
Four acyclic guanosine analogs, the (R) and (S) enantiomers of 9-(3,4-dihydroxybutyl)guanine, 9-(4-hydroxybutyl)guanine, and acyclovir were compared in enzyme kinetic experiments, using purified herpes simplex virus type 2 thymidine kinase. All four analogs showed competitive patterns of inhibition...
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| Publicado no: | Antimicrob Agents Chemother |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
1984
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185571/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6329085/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.25.4.524 |
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