Phosphorylation of four acyclic guanosine analogs by herpes simplex virus type 2 thymidine kinase.

Four acyclic guanosine analogs, the (R) and (S) enantiomers of 9-(3,4-dihydroxybutyl)guanine, 9-(4-hydroxybutyl)guanine, and acyclovir were compared in enzyme kinetic experiments, using purified herpes simplex virus type 2 thymidine kinase. All four analogs showed competitive patterns of inhibition...

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Vydáno v:	Antimicrob Agents Chemother
Hlavní autoři:	Larsson, A, Tao, P Z
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 1984
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185571/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6329085/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.25.4.524
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