Characterization of a varicella-zoster virus variant with altered thymidine kinase activity.

A varicella-zoster virus (VZV) strain resistant to 5-iodo-2'-deoxyuridine (IdUrd) and 5-bromo-2'-deoxyuridine (BrdUrd) but sensitive to (E)-5-(2-bromovinyl)-2'-deoxyuridine (BVdUrd) and (E)-5-(2-iodovinyl)-2'-deoxyuridine (IVdUrd) was isolated. The 2'-deoxythymidine (dThd) kinase of this mutant (Ito...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Shigeta, S, Mori, S, Yokota, T, Konno, K, De Clercq, E
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1986
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC180499/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3015014/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.29.6.1053
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