Evolution of Integrase Resistance During Failure of Integrase Inhibitor-Based Antiretroviral Therapy

BACKGROUND: Although integrase inhibitors are highly effective in the management of drug-resistant HIV, some patients fail to achieve durable viral suppression. The long-term consequences of integrase inhibitor failure have not been well-defined. METHODS: We identified 29 individuals who exhibited e...

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Main Authors: Hatano, Hiroyu, Lampiris, Harry, Fransen, Signe, Gupta, Soumi, Huang, Wei, Hoh, Rebecca, Martin, Jeffrey N., Lalezari, Jacob, Bangsberg, David, Petropoulos, Christos, Deeks, Steven G.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890029/
https://ncbi.nlm.nih.gov/pubmed/20300008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0b013e3181c42ea4
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