Nucleophosmin and nucleolin regulate K-Ras signaling

Ras proteins are laterally segregated into transient nanoclusters on the plasma membrane, a property essential for high fidelity signal transduction through the MAPK pathway. From a proteomic screen we identified nucleophosmin (NPM) and nucleolin as two novel regulators of K-Ras plasma membrane inte...

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Bibliographic Details
Main Authors: Inder, Kerry L, Hill, Michelle M, Hancock, John F
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889983/
https://ncbi.nlm.nih.gov/pubmed/20585519
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