In vivo Regulation of the Allergic Response by the Interleukin 4 Receptor Alpha Chain Immunoreceptor Tyrosine-based Inhibitory Motif

BACKGROUND: Signaling by IL-4 and IL-13 via the IL-4 receptor alpha chain (IL-4Rα) plays a critical role in the pathology of allergic diseases. The IL-4Rα is endowed with an immunoreceptor tyrosine-based inhibitory motif (ITIM), centered on tyrosine 709 (Y709) in the cytoplasmic domain, that binds a...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Tachdjian, Raffi, Khatib, Shadi Al, Schwinglshackl, Andreas, Kim, Hong Sook, Chen, Andrew, Blasioli, Julie, Mathias, Clinton, Kim, Hye-Young, Umetsu, Dale T., Oettgen, Hans C., Chatila, Talal A.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889905/
https://ncbi.nlm.nih.gov/pubmed/20392476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2010.01.054
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares