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The distribution of the therapeutic monoclonal antibodies cetuximab and trastuzumab within solid tumors

BACKGROUND: Poor distribution of some anticancer drugs in solid tumors may limit their anti-tumor activity. METHODS: Here we used immunohistochemistry to quantify the distribution of the therapeutic monoclonal antibodies cetuximab and trastuzumab in relation to blood vessels and to regions of hypoxi...

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Autors principals: Lee, Carol M, Tannock, Ian F
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889896/
https://ncbi.nlm.nih.gov/pubmed/20525277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-255
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