Estradiol suppresses tissue androgens and prostate cancer growth in castration resistant prostate cancer

BACKGROUND: Estrogens suppress tumor growth in prostate cancer which progresses despite anorchid serum androgen levels, termed castration resistant prostate cancers (CRPC), although the mechanisms are unclear. We hypothesize that estrogen inhibits CRPC in anorchid animals by suppressing tumoral andr...

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Bibliografiske detaljer
Main Authors: Montgomery, Bruce, Nelson, Peter S, Vessella, Robert, Kalhorn, Tom, Hess, David, Corey , Eva
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2010
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889894/
https://ncbi.nlm.nih.gov/pubmed/20509933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-244
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