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Estradiol suppresses tissue androgens and prostate cancer growth in castration resistant prostate cancer

BACKGROUND: Estrogens suppress tumor growth in prostate cancer which progresses despite anorchid serum androgen levels, termed castration resistant prostate cancers (CRPC), although the mechanisms are unclear. We hypothesize that estrogen inhibits CRPC in anorchid animals by suppressing tumoral andr...

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Detalhes bibliográficos
Main Authors: Montgomery, Bruce, Nelson, Peter S, Vessella, Robert, Kalhorn, Tom, Hess, David, Corey , Eva
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889894/
https://ncbi.nlm.nih.gov/pubmed/20509933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-244
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