Estradiol suppresses tissue androgens and prostate cancer growth in castration resistant prostate cancer

BACKGROUND: Estrogens suppress tumor growth in prostate cancer which progresses despite anorchid serum androgen levels, termed castration resistant prostate cancers (CRPC), although the mechanisms are unclear. We hypothesize that estrogen inhibits CRPC in anorchid animals by suppressing tumoral andr...

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Autors principals: Montgomery, Bruce, Nelson, Peter S, Vessella, Robert, Kalhorn, Tom, Hess, David, Corey , Eva
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2010
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889894/
https://ncbi.nlm.nih.gov/pubmed/20509933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-244
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