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MicroRNA-122 Modulates the Rhythmic Expression Profile of the Circadian Deadenylase Nocturnin in Mouse Liver

Nocturnin is a circadian clock-regulated deadenylase thought to control mRNA expression post-transcriptionally through poly(A) tail removal. The expression of Nocturnin is robustly rhythmic in liver at both the mRNA and protein levels, and mice lacking Nocturnin are resistant to diet-induced obesity...

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Detalhes bibliográficos
Main Authors: Kojima, Shihoko, Gatfield, David, Esau, Christine C., Green, Carla B.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889834/
https://ncbi.nlm.nih.gov/pubmed/20582318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011264
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