Integration of microRNA miR-122 in hepatic circadian gene expression

In liver, most metabolic pathways are under circadian control, and hundreds of protein-encoding genes are thus transcribed in a cyclic fashion. Here we show that rhythmic transcription extends to the locus specifying miR-122, a highly abundant, hepatocyte-specific microRNA. Genetic loss-of-function...

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Detalhes bibliográficos
Main Authors: Gatfield, David, Le Martelot, Gwendal, Vejnar, Charles E., Gerlach, Daniel, Schaad, Olivier, Fleury-Olela, Fabienne, Ruskeepää, Anna-Liisa, Oresic, Matej, Esau, Christine C., Zdobnov, Evgeny M., Schibler, Ueli
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2009
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701584/
https://ncbi.nlm.nih.gov/pubmed/19487572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1781009
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