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Loss of Nocturnin, a circadian deadenylase, confers resistance to hepatic steatosis and diet-induced obesity

The mammalian circadian system consists of a central oscillator in the suprachiasmatic nucleus of the hypothalamus, which coordinates peripheral clocks in organs throughout the body. Although circadian clocks control the rhythmic expression of a large number of genes involved in metabolism and other...

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Главные авторы: Green, Carla B., Douris, Nicholas, Kojima, Shihoko, Strayer, Carl A., Fogerty, Joseph, Lourim, David, Keller, Susanna R., Besharse, Joseph C.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2007
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1871564/
https://ncbi.nlm.nih.gov/pubmed/17517647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0702448104
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