Fibroblast Growth Factor 21 Action in the Brain Increases Energy Expenditure and Insulin Sensitivity in Obese Rats

OBJECTIVE: The hormone fibroblast growth factor 21 (FGF21) exerts diverse, beneficial effects on energy balance and insulin sensitivity when administered systemically to rodents with diet-induced obesity (DIO). The current studies investigate whether central FGF21 treatment recapitulates these effec...

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Detalhes bibliográficos
Main Authors: Sarruf, David A., Thaler, Joshua P., Morton, Gregory J., German, Jonathan, Fischer, Jonathan D., Ogimoto, Kayoko, Schwartz, Michael W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2010
Assuntos:
Pharmacology and Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889784/
https://ncbi.nlm.nih.gov/pubmed/20357365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-1878
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