An FGF21-Adiponectin-Ceramide Axis Controls Energy Expenditure and Insulin Action in Mice

FGF21, a member of the fibroblast growth factor (FGF) superfamily has recently emerged as a novel regulator of metabolism and energy utilization. However, the exact mechanism(s) whereby FGF21 mediates its actions have not been elucidated. There is considerable evidence that insulin resistance may ar...

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Bibliographische Detailangaben
Hauptverfasser: Holland, William L., Adams, Andrew C., Brozinick, Joseph T., Bui, Hai H., Miyauchi, Yukiko, Kusminski, Christine M., Bauer, Steven M., Wade, Mark, Singhal, Esha, Cheng, Christine C., Volk, Katherine, Kuo, Ming-Shang, Gordillo, Ruth, Kharitonenkov, Alexei, Scherer, Philipp E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3667496/
https://ncbi.nlm.nih.gov/pubmed/23663742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2013.03.019
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