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FGF19 and FGF21: In NASH we trust

OBJECTIVE: FGF19 and FGF21 have shown therapeutic promise since their discovery, attested by the fact there are at least 5 assets that activate the FGFR/KLB pathway and one FGF19 analog in clinical development. METHODS: We performed a detailed analyses of published preclinical and clinical data to o...

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Detalhes bibliográficos
Publicado no:Mol Metab
Main Authors: Talukdar, Saswata, Kharitonenkov, Alexei
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8085573/
https://ncbi.nlm.nih.gov/pubmed/33383173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2020.101152
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