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Regulation of Retinal Function but Nonrescue of Vision in RPE65-deficient Dogs Treated With Doxycycline-regulatable AAV Vectors

In previous studies, we demonstrated that recombinant adeno-associated virus (rAAV)-mediated gene transfer of the doxycycline (Dox)-regulatable system allows for the regulation of erythropoietin (EPO) expression in the retina of nonhuman primates after intravenous or oral administration of Dox. In a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lhériteau, Elsa, Libeau, Lyse, Mendes-Madeira, Alexandra, Deschamps, Jack-Yves, Weber, Michel, Le Meur, Guylène, Provost, Nathalie, Guihal, Caroline, Moullier, Philippe, Rolling, Fabienne
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889751/
https://ncbi.nlm.nih.gov/pubmed/20354505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.46
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