Detection of Intact rAAV Particles up to 6 Years After Successful Gene Transfer in the Retina of Dogs and Primates

Gene transfer to the retina using recombinant adeno-associated viral (rAAV) vectors has proven to be an effective option for the treatment of retinal degenerative diseases in several animal models and has recently advanced into clinical trials in humans. To date, intracellular trafficking of AAV vec...

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Bibliographic Details
Main Authors: Stieger, Knut, Schroeder, Josef, Provost, Nathalie, Mendes-Madeira, Alexandra, Belbellaa, Brahim, Meur, Guylène Le, Weber, Michel, Deschamps, Jack-Yves, Lorenz, Birgit, Moullier, Philippe, Rolling, Fabienne
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2008
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835079/
https://ncbi.nlm.nih.gov/pubmed/19107120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2008.283
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