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Inhibition of Multiple Protective Signaling Pathways and Ad.5/3 Delivery Enhances mda-7/IL-24 Therapy of Malignant Glioma

We have explored the mechanism by which inhibition of multiple cytoprotective cell-signaling pathways enhance melanoma differentiation-associated gene-7/interleukin-24 (mda-7/IL-24) toxicity toward invasive primary human glioblastoma multiforme (GBM) cells, and whether improving adenoviral infectivi...

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Detalhes bibliográficos
Main Authors: Hamed, Hossein A, Yacoub, Adly, Park, Margaret A, Eulitt, Patrick J, Dash, Rupesh, Sarkar, Devanand, Dmitriev, Igor P, Lesniak, Maciej S, Shah, Khalid, Grant, Steven, Curiel, David T, Fisher, Paul B, Dent, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889737/
https://ncbi.nlm.nih.gov/pubmed/20179672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.29
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