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Rescue of the spinal muscular atrophy phenotype in a mouse model by early postnatal delivery of SMN

Spinal muscular atrophy (SMA), the most common autosomal recessive neurodegenerative disease affecting children, results in impaired motor neuron function1. Despite knowledge of the pathogenic role of decreased survival motor neuron (SMN) protein levels, efforts to increase SMN have not resulted in...

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Main Authors:	Foust, Kevin D, Wang, Xueyong, McGovern, Vicki L, Braun, Lyndsey, Bevan, Adam K, Haidet, Amanda M, Le, Thanh T, Morales, Pablo R, Rich, Mark M, Burghes, Arthur H M, Kaspar, Brian K
Formáid:	Artigo
Teanga:	Inglês
Foilsithe:	2010
Ábhair:	Article
Rochtain Ar Líne:	https://ncbi.nlm.nih.gov/pmc/articles/PMC2889698/ https://ncbi.nlm.nih.gov/pubmed/20190738 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.1610
Clibeanna:	Cuir Clib Leis Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!

Rescue of the spinal muscular atrophy phenotype in a mouse model by early postnatal delivery of SMN

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