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The neuromuscular impact of symptomatic SMN restoration in a mouse model of spinal muscular atrophy

BACKGROUND: Significant advances in the development of SMN-restoring therapeutics have occurred since 2010 when very effective biological treatments were reported in mouse models of spinal muscular atrophy. As these treatments are applied in human clinical trials, there is pressing need to define qu...

詳細記述

保存先:
書誌詳細
出版年:Neurobiol Dis
主要な著者: Arnold, W. David, McGovern, Vicki L., Sanchez, Benjamin, Li, Jia, Corlett, Kaitlyn M., Kolb, Stephen J., Rutkove, Seward B., Burghes, Arthur H.
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4724465/
https://ncbi.nlm.nih.gov/pubmed/26733414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2015.12.014
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