Učitavanje...
The Hippo–Salvador pathway restrains hepatic oval cell proliferation, liver size, and liver tumorigenesis
Loss of Hippo signaling in Drosophila leads to tissue overgrowth as a result of increased cell proliferation and decreased cell death. YAP (a homolog of Drosophila Yorkie and target of the Hippo pathway) was recently implicated in control of organ size, epithelial tissue development, and tumorigenes...
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| Glavni autori: | , , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2010
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2889558/ https://ncbi.nlm.nih.gov/pubmed/20404163 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0912203107 |
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