The Hippo–Salvador pathway restrains hepatic oval cell proliferation, liver size, and liver tumorigenesis

Loss of Hippo signaling in Drosophila leads to tissue overgrowth as a result of increased cell proliferation and decreased cell death. YAP (a homolog of Drosophila Yorkie and target of the Hippo pathway) was recently implicated in control of organ size, epithelial tissue development, and tumorigenes...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Lee, Kwang-Pyo, Lee, Joo-Hyeon, Kim, Tae-Shin, Kim, Tack-Hoon, Park, Hee-Dong, Byun, Jin-Seok, Kim, Min-Chul, Jeong, Won-Il, Calvisi, Diego F., Kim, Jin-Man, Lim, Dae-Sik
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2010
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889558/
https://ncbi.nlm.nih.gov/pubmed/20404163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0912203107
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg