The Hippo–Salvador pathway restrains hepatic oval cell proliferation, liver size, and liver tumorigenesis

Loss of Hippo signaling in Drosophila leads to tissue overgrowth as a result of increased cell proliferation and decreased cell death. YAP (a homolog of Drosophila Yorkie and target of the Hippo pathway) was recently implicated in control of organ size, epithelial tissue development, and tumorigenes...

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Dades bibliogràfiques
Autors principals: Lee, Kwang-Pyo, Lee, Joo-Hyeon, Kim, Tae-Shin, Kim, Tack-Hoon, Park, Hee-Dong, Byun, Jin-Seok, Kim, Min-Chul, Jeong, Won-Il, Calvisi, Diego F., Kim, Jin-Man, Lim, Dae-Sik
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2010
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889558/
https://ncbi.nlm.nih.gov/pubmed/20404163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0912203107
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