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Preclinical model of organotypic culture for pharmacodynamic profiling of human tumors

Predicting drug response in cancer patients remains a major challenge in the clinic. We have perfected an ex vivo, reproducible, rapid and personalized culture method to investigate antitumoral pharmacological properties that preserves the original cancer microenvironment. Response to signal transdu...

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Autors principals: Vaira, Valentina, Fedele, Giuseppe, Pyne, Saumyadipta, Fasoli, Ester, Zadra, Giorgia, Bailey, Dyane, Snyder, Eric, Faversani, Alice, Coggi, Guido, Flavin, Richard, Bosari, Silvano, Loda, Massimo
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889536/
https://ncbi.nlm.nih.gov/pubmed/20404174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0907676107
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