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Preclinical model of organotypic culture for pharmacodynamic profiling of human tumors

Predicting drug response in cancer patients remains a major challenge in the clinic. We have perfected an ex vivo, reproducible, rapid and personalized culture method to investigate antitumoral pharmacological properties that preserves the original cancer microenvironment. Response to signal transdu...

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Detalhes bibliográficos
Main Authors: Vaira, Valentina, Fedele, Giuseppe, Pyne, Saumyadipta, Fasoli, Ester, Zadra, Giorgia, Bailey, Dyane, Snyder, Eric, Faversani, Alice, Coggi, Guido, Flavin, Richard, Bosari, Silvano, Loda, Massimo
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889536/
https://ncbi.nlm.nih.gov/pubmed/20404174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0907676107
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