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Metabolic alterations and targeted therapies in prostate cancer
Cancer cells synthesize de novo large amounts of fatty acids and cholesterol, irrespective of the circulating lipid levels and benefit from this increased lipid synthesis in terms of growth advantage, self-survival and drug resistance. Key lipogenic alterations that commonly occur in prostate cancer...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3197856/ https://ncbi.nlm.nih.gov/pubmed/21125681 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.2809 |
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