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Metabolic alterations and targeted therapies in prostate cancer

Cancer cells synthesize de novo large amounts of fatty acids and cholesterol, irrespective of the circulating lipid levels and benefit from this increased lipid synthesis in terms of growth advantage, self-survival and drug resistance. Key lipogenic alterations that commonly occur in prostate cancer...

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Autors principals: Flavin, Richard, Zadra, Giorgia, Loda, Massimo
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3197856/
https://ncbi.nlm.nih.gov/pubmed/21125681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.2809
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