Survivin family proteins as novel molecular determinants of doxorubicin resistance in organotypic human breast tumors

INTRODUCTION: The molecular determinants of breast cancer resistance to first-line anthracycline-containing chemotherapy are unknown. METHODS: We examined the response to doxorubicin of organotypic cultures of primary human breast tumors ex vivo with respect to cell proliferation, DNA damage and mod...

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Main Authors: Faversani, Alice, Vaira, Valentina, Moro, Giacomina P, Tosi, Delfina, Lopergolo, Alessia, Schultz, David C, Rivadeneira, Dayana, Altieri, Dario C, Bosari, Silvano
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4076638/
https://ncbi.nlm.nih.gov/pubmed/24886669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3666
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