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MLCK-dependent exchange and actin binding region-dependent anchoring of ZO-1 regulate tight junction barrier function

The perijunctional actomyosin ring contributes to myosin light chain kinase (MLCK)-dependent tight junction regulation. However, the specific protein interactions involved in this process are unknown. To test the hypothesis that molecular remodeling contributes to barrier regulation, tight junction...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Yu, Dan, Marchiando, Amanda M., Weber, Christopher R., Raleigh, David R., Wang, Yingmin, Shen, Le, Turner, Jerrold R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889526/
https://ncbi.nlm.nih.gov/pubmed/20404178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0908869107
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