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Actin Depolymerization Disrupts Tight Junctions via Caveolae-mediated Endocytosis

The tight junction (TJ) determines epithelial barrier function. Actin depolymerization disrupts TJ structure and barrier function, but the mechanisms of this effect remain poorly understood. The goal of this study was to define these mechanisms. Madin-Darby canine kidney (MDCK) cells expressing enha...

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Detalhes bibliográficos
Main Authors: Shen, Le, Turner, Jerrold R.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1196308/
https://ncbi.nlm.nih.gov/pubmed/15958494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E04-12-1089
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