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Actin Depolymerization Disrupts Tight Junctions via Caveolae-mediated Endocytosis

The tight junction (TJ) determines epithelial barrier function. Actin depolymerization disrupts TJ structure and barrier function, but the mechanisms of this effect remain poorly understood. The goal of this study was to define these mechanisms. Madin-Darby canine kidney (MDCK) cells expressing enha...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Shen, Le, Turner, Jerrold R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Cell Biology 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1196308/
https://ncbi.nlm.nih.gov/pubmed/15958494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E04-12-1089
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