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IL-23 suppresses innate immune response independently of IL-17A during carcinogenesis and metastasis

IL-23 is an important molecular driver of Th17 cells and has strong tumor-promoting proinflammatory activity postulated to occur via adaptive immunity. Conversely, more recently it has been reported that IL-17A elicits a protective inflammation that promotes the activation of tumor-specific CD8(+) T...

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Autori principali: Teng, Michele W. L., Andrews, Daniel M., McLaughlin, Nicole, von Scheidt, Bianca, Ngiow, Shin Foong, Möller, Andreas, Hill, Geoffrey R., Iwakura, Yoichiro, Oft, Martin, Smyth, Mark J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889517/
https://ncbi.nlm.nih.gov/pubmed/20404142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1003251107
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