Common Functional Genetic Variants in Catecholamine Storage Vesicle Protein Promoter Motifs Interact to Trigger Systemic Hypertension

OBJECTIVES: The purpose of this study was to explore transcriptional mechanisms whereby genetic variation in the CHGB promoter influence BP and hypertension. BACKGROUND: Hypertension is a complex trait in which deranged autonomic control of the circulation may be an etiological culprit. Chromogranin...

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Autores principales: Zhang, Kuixing, Rao, Fangwen, Wang, Lei, Rana, Brinda K., Ghosh, Sajalendu, Mahata, Manjula, Salem, Rany M., Rodriguez-Flores, Juan L., Fung, Maple M., Waalen, Jill, Tayo, Bamidele, Taupenot, Laurent, Mahata, Sushil K., O'Connor, Daniel T.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889490/
https://ncbi.nlm.nih.gov/pubmed/20359597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2009.11.064
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