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Deletion of Braun lipoprotein gene (lpp) and curing of plasmid pPCP1 dramatically alter the virulence of Yersinia pestis CO92 in a mouse model of pneumonic plague

Deletion of the murein (Braun) lipoprotein gene, lpp, attenuates the Yersinia pestis CO92 strain in mouse models of bubonic and pneumonic plague. In this report, we characterized the virulence of strains from which the plasminogen activating protease (pla)-encoding pPCP1 plasmid was cured from eithe...

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主要な著者: Agar, Stacy L., Sha, Jian, Baze, Wallace B., Erova, Tatiana E., Foltz, Sheri M., Suarez, Giovanni, Wang, Shaofei, Chopra, Ashok K.
フォーマット: Artigo
言語:Inglês
出版事項: Microbiology Society 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889417/
https://ncbi.nlm.nih.gov/pubmed/19589835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/mic.0.029124-0
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