Deletion of Braun lipoprotein gene (lpp) and curing of plasmid pPCP1 dramatically alter the virulence of Yersinia pestis CO92 in a mouse model of pneumonic plague

Deletion of the murein (Braun) lipoprotein gene, lpp, attenuates the Yersinia pestis CO92 strain in mouse models of bubonic and pneumonic plague. In this report, we characterized the virulence of strains from which the plasminogen activating protease (pla)-encoding pPCP1 plasmid was cured from eithe...

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Detalhes bibliográficos
Main Authors: Agar, Stacy L., Sha, Jian, Baze, Wallace B., Erova, Tatiana E., Foltz, Sheri M., Suarez, Giovanni, Wang, Shaofei, Chopra, Ashok K.
Formato: Artigo
Idioma:Inglês
Publicado em: Microbiology Society 2009
Assuntos:
Microbial Pathogenicity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889417/
https://ncbi.nlm.nih.gov/pubmed/19589835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/mic.0.029124-0
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