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Conversion of Th2 memory cells into Foxp3(+) regulatory T cells suppressing Th2-mediated allergic asthma

Genetic and epigenetic programming of T helper (Th) cell subsets during their polarization from naive Th cells establishes long-lived memory Th cells that stably maintain their lineage signatures. However, whether memory Th cells can be redifferentiated into another Th lineage is unclear. In this st...

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Hlavní autoři: Kim, Byung-Seok, Kim, Il-Kyu, Park, Young-Jun, Kim, Yun-Sun, Kim, Yeon-Jeong, Chang, Woo-Sung, Lee, Yoon-Sook, Kweon, Mi-Na, Chung, Yeonseok, Kang, Chang-Yuil
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889331/
https://ncbi.nlm.nih.gov/pubmed/20421479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0911756107
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