SWIM STRESS ENHANCES NOCICEPTIN/ORPHANIN FQ-INDUCED INHIBITION OF RAT DORSAL RAPHE NUCLEUS ACTIVITY IN VIVO AND IN VITRO: ROLE OF CORTICOTROPIN-RELEASING FACTOR

The effects of nociceptin/orphanin FQ on putative serotonin (5HT) neurons of the dorsal raphe nucleus (DRN), known to modulate the behavioral responses to stress, were investigated in vivo and in vitro. In DRN slices from unstressed rats, nociceptin/orphanin FQ concentration-dependently inhibited th...

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Hauptverfasser: Nazzaro, Cristiano, Barbieri, Mario, Varani, Katia, Beani, Lorenzo, Valentino, Rita J., Siniscalchi, Anna
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889245/
https://ncbi.nlm.nih.gov/pubmed/19747494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2009.09.004
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