SWIM STRESS ENHANCES NOCICEPTIN/ORPHANIN FQ-INDUCED INHIBITION OF RAT DORSAL RAPHE NUCLEUS ACTIVITY IN VIVO AND IN VITRO: ROLE OF CORTICOTROPIN-RELEASING FACTOR

The effects of nociceptin/orphanin FQ on putative serotonin (5HT) neurons of the dorsal raphe nucleus (DRN), known to modulate the behavioral responses to stress, were investigated in vivo and in vitro. In DRN slices from unstressed rats, nociceptin/orphanin FQ concentration-dependently inhibited th...

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Detalhes bibliográficos
Main Authors: Nazzaro, Cristiano, Barbieri, Mario, Varani, Katia, Beani, Lorenzo, Valentino, Rita J., Siniscalchi, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889245/
https://ncbi.nlm.nih.gov/pubmed/19747494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2009.09.004
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