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Cystatin C protects neuronal cells from amyloid β-induced toxicity

Multiple studies suggest that cystatin C (CysC) has a role in Alzheimer's disease (AD) and a decrease in CysC secretion is linked to the disease in patients with a polymorphism in the CysC gene. CysC binds amyloid β (Aβ) and inhibits formation of Aβ fibrils and oligomers both in vitro and in mo...

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Detalles Bibliográficos
Main Authors: Tizon, Belen, Ribe, Elena M., Mi, Weiqian, Troy, Carol M., Levy, Efrat
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889175/
https://ncbi.nlm.nih.gov/pubmed/20157244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-2010-1291
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