Induction of Autophagy by Cystatin C: A Mechanism That Protects Murine Primary Cortical Neurons and Neuronal Cell Lines

Cystatin C (CysC) expression in the brain is elevated in human patients with epilepsy, in animal models of neurodegenerative conditions, and in response to injury, but whether up-regulated CysC expression is a manifestation of neurodegeneration or a cellular repair response is not understood. This s...

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Main Authors: Tizon, Belen, Sahoo, Susmita, Yu, Haung, Gauthier, Sebastien, Kumar, Asok R., Mohan, Panaiyur, Figliola, Matthew, Pawlik, Monika, Grubb, Anders, Uchiyama, Yasuo, Bandyopadhyay, Urmi, Cuervo, Ana Maria, Nixon, Ralph A., Levy, Efrat
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2010
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2843718/
https://ncbi.nlm.nih.gov/pubmed/20352108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009819
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