Cystatin C Rescues Degenerating Neurons in a Cystatin B-Knockout Mouse Model of Progressive Myoclonus Epilepsy

In vitro studies have shown that cystatin C (CysC) is neuroprotective. Here we demonstrate that CysC is neuroprotective in vivo, in a mouse model of the inherited neurodegenerative disorder, progressive myoclonic epilepsy type 1 (EPM1). Loss-of-function mutations in the cystatin B (CysB) gene, an in...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Kaur, Gurjinder, Mohan, Panaiyur, Pawlik, Monika, DeRosa, Steven, Fajiculay, Jay, Che, Shaoli, Grubb, Anders, Ginsberg, Stephen D., Nixon, Ralph A., Levy, Efrat
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Investigative Pathology 2010
Konular:
Regular Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2966785/
https://ncbi.nlm.nih.gov/pubmed/20889561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.100461
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller