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Complexes of Amyloid-β and Cystatin C in the Human Central Nervous System
A role for cystatin C (CysC) in the pathogenesis of Alzheimer’s disease (AD) has been suggested by the genetic linkage of a CysC gene (CST3) polymorphism with late-onset AD, the co-localization of CysC with amyloid-β (Aβ) in AD brains, and binding of CysC to soluble Aβ in vitro and in mouse models o...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2792995/ https://ncbi.nlm.nih.gov/pubmed/19584436 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-2009-1147 |
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