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Direct role for the RNA polymerase domain of T7 primase in primer delivery
Gene 4 protein (gp4) encoded by bacteriophage T7 contains a C-terminal helicase and an N-terminal primase domain. After synthesis of tetraribonucleotides, gp4 must transfer them to the polymerase for use as primers to initiate DNA synthesis. In vivo gp4 exists in two molecular weight forms, a 56-kDa...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2889121/ https://ncbi.nlm.nih.gov/pubmed/20439755 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1004220107 |
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