Hepatitis B virus core antigen determines viral persistence in a C57BL/6 mouse model

We recently developed a mouse model of hepatitis B virus (HBV) persistence, in which a single i.v. hydrodynamic injection of HBV DNA to C57BL/6 mice allows HBV replication and induces a partial immune response, so that about 20–30% of the mice carry HBV for more than 6 months. The model was used to...

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Bibliografiske detaljer
Main Authors: Lin, Yi-Jiun, Huang, Li-Rung, Yang, Hung-Chih, Tzeng, Horng-Tay, Hsu, Ping-Ning, Wu, Hui-Lin, Chen, Pei-Jer, Chen, Ding-Shinn
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2010
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889105/
https://ncbi.nlm.nih.gov/pubmed/20439715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1004762107
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