PD-1 Blockage Reverses Immune Dysfunction and Hepatitis B Viral Persistence in a Mouse Animal Model

Persistent hepatitis B viral (HBV) infection results in chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma (HCC). Recent studies in animal models of viral infection indicate that the interaction between the inhibitory receptor, programmed death (PD)-1, on lymphocytes and its ligand (PD...

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Detalhes bibliográficos
Main Authors: Tzeng, Horng-Tay, Tsai, Hwei-Fang, Liao, Hsiu-Jung, Lin, Yi-Jiun, Chen, Lieping, Chen, Pei-Jer, Hsu, Ping-Ning
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3382233/
https://ncbi.nlm.nih.gov/pubmed/22761734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039179
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