In situ recognition of autoantigen as an essential gatekeeper in autoimmune CD8(+) T cell inflammation

A current paradigm states that non-antigen-specific inflammatory cues attract noncognate, bystander T cell specificities to sites of infection and autoimmune inflammation. Here we show that cues emanating from a tissue undergoing spontaneous autoimmune inflammation cannot recruit naive or activated...

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Bibliographic Details
Main Authors: Wang, Jinguo, Tsai, Sue, Shameli, Afshin, Yamanouchi, Jun, Alkemade, Gonnie, Santamaria, Pere
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2010
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889101/
https://ncbi.nlm.nih.gov/pubmed/20439719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0913835107
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