Endoplasmic Reticulum Stress Caused by Overexpression of Islet-Specific Glucose-6-Phosphatase Catalytic Subunit-Related Protein in Pancreatic Beta-Cells

The high rate of protein synthesis in β-cells renders them susceptible to endoplasmic reticulum (ER) stress, a condition that can be aggravated by additional imbalances in ER homeostasis and could potentially contribute to the pathogenesis of type-1 and type-2 diabetes. Islet-specific glucose-6-phos...

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Hlavní autoři: Shameli, Afshin, Yamanouchi, Jun, Thiessen, Shari, Santamaria, Pere
Médium: Artigo
Jazyk:Inglês
Vydáno: SBDR - Society for Biomedical Diabetes Research 2007
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892522/
https://ncbi.nlm.nih.gov/pubmed/17565413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1900/RDS.2007.4.25
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