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The M(3)-muscarinic receptor regulates learning and memory in a receptor phosphorylation/arrestin-dependent manner

Degeneration of the cholinergic system is considered to be the underlying pathology that results in the cognitive deficit in Alzheimer's disease. This pathology is thought to be linked to a loss of signaling through the cholinergic M(1)-muscarinic receptor subtype. However, recent studies have...

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Main Authors: Poulin, Benoit, Butcher, Adrian, McWilliams, Phillip, Bourgognon, Julie-Myrtille, Pawlak, Robert, Kong, Kok Choi, Bottrill, Andrew, Mistry, Sharad, Wess, Jürgen, Rosethorne, Elizabeth M., Charlton, Steven J., Tobin, Andrew B.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889095/
https://ncbi.nlm.nih.gov/pubmed/20439723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914801107
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