Phosphorylation and regulation of a G protein–coupled receptor by protein kinase CK2

We demonstrate a role for protein kinase casein kinase 2 (CK2) in the phosphorylation and regulation of the M(3)-muscarinic receptor in transfected cells and cerebellar granule neurons. On agonist occupation, specific subsets of receptor phosphoacceptor sites (which include the SASSDEED motif in the...

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Detalhes bibliográficos
Main Authors: Torrecilla, Ignacio, Spragg, Elizabeth J., Poulin, Benoit, McWilliams, Phillip J., Mistry, Sharad C., Blaukat, Andree, Tobin, Andrew B.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2007
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064117/
https://ncbi.nlm.nih.gov/pubmed/17403928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200610018
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