Expression of the yeast NADH dehydrogenase Ndi1 in Drosophila confers increased lifespan independently of dietary restriction

Mutations in mitochondrial oxidative phosphorylation complex I are associated with multiple pathologies, and complex I has been proposed as a crucial regulator of animal longevity. In yeast, the single-subunit NADH dehydrogenase Ndi1 serves as a non-proton-translocating alternative enzyme that repla...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Sanz, Alberto, Soikkeli, Mikko, Portero-Otín, Manuel, Wilson, Angela, Kemppainen, Esko, McIlroy, George, Ellilä, Simo, Kemppainen, Kia K., Tuomela, Tea, Lakanmaa, Matti, Kiviranta, Essi, Stefanatos, Rhoda, Dufour, Eric, Hutz, Bettina, Naudí, Alba, Jové, Mariona, Zeb, Akbar, Vartiainen, Suvi, Matsuno-Yagi, Akemi, Yagi, Takao, Rustin, Pierre, Pamplona, Reinald, Jacobs, Howard T.
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2010
נושאים:
Biological Sciences
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889079/
https://ncbi.nlm.nih.gov/pubmed/20435911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0911539107
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!

פריטים דומים